• [Archive]
• Journal of Pharmacopuncture
• pISSN : 2093-6966
• eISSN : 2234-6856
• DB Construction : 59 Issues, 667 Articles
Year
Issues
Articles
1 Title
Keywords Hominis Placenta; Sleep pattern disturbances; Herbal acupuncture
Author(s) Lee, Chae-Wooi; Kim, Hong-K; Youn, Hyoun-Min
 Abstract Objectives : This study has been designed and performed to identify the effect of Hominis Placenta herbal acupuncture which is usually used in reducing sleep pattern disturbances. Methods : The study subjects studied included 48 patients who were admitted in hospital located in Pusan, and they were classified into 2 groups : 25 patients in the experimental group who injected Hominis Placenta herbal acupuncture and 23 patients in the control group who were treated by acupuncture. The both group injected on $\small{GB_{20}}$, $\small{GB_{12}}$ and $\small{GB_{20}}$ for 5 days without medicine. The sleep pattern disturbance score was measured by using 15 questions according to Korean Sleep Scale A(Oh, Jin Joo. Song, Mi. Soon. Kim, Shin Mi. 1998). Results & conclusions : The sleep pattern disturbance score of the experimental group who injected Hominis Placenta herbal acupuncture was significantly lower than that of the control group(t=7.00 p=.00). These results provided that Hominis Placenta herbal acupuncture of $\small{GB_{20}}$, $\small{GB_{12}}$ and HT, was effective for relieving sleep pattern disturbances, it is need mere sample's number and more treatment's duration.
2 Title
Keywords Scolopendrid herbal acupucture; Carpal Tunnel Syndrome; random
Author(s) Lim, Jeong-A; Kim, Sung-Nam; Lee, Sung-Young; Moon, Hyung-Cheol; Kim, Sung-Chul
 Abstract Objectives : This study is performed for the purpose of examining into the efficacy of the scolopendrid herbal acupucture which has been used among the Korean people for the Carpal tunnel syndrome. Methods : 40 carpal tunnel syndrome patients who visited Won-kwang University Hospital during the period from January 1998 to December 2004 were analysed for clinical manifestations. After we divided patients into two classes at random, we treated them with scolopendrid herbal acupucture or not. Treatment efficiency was monitored through VAS(Visual Analog Scale) and clinical symptom. Conclusion : We brought to the conclusion that the scolopendrid herbal acupucture has possibility to be efficient to cure the carpal tunnel syndrome patients. So we suggest the possibility to use this new remedy for the carpal tunnel syndrome.
3 Title
Keywords Bee Venom; Anti-Bee Venom; LD50; Acute toxicity; H-E stain; IgY
Author(s) Kwon, Ki-Rok; Lee, Kwang-Ho; Park, Won-Pil
 Abstract Objectives : To observe physiological anti-body effects of anti-BV, acute toxic response, measurement of $\small{LD_{50}}$, and the effects of anti-body were evaluated. Methods : $\small{LD_{50}}$ of Anti-Bee Venom were measured, and to analyze acute toxic responses, weight, and the anti-body effects various concentrations of Anti-BV were diluted and the survival rate was measured. Cell blood count (CBC), liver, spleen, and kidney pathologies were observed from the histological aspects. Results : Experiment was conducted to observe Anti-BV as the anti-body to the bee venom and the following results were obtained : 1.anti-BV was injected intraperitoneally and no toxic responses were witnessed. All of the experiment subjects stayed alive during the experiment, making $\small{LD_{50}}$ analysis impossible. 2.Anti-BV was injected intraperitoneally in mice and no significant weight changes were measured between the control group and the experiment groups. 3. Measuring the concentration dependent survival rate, the highest survival rate was at the concentration of $\small{1.25{\times}10^2mg/kg}$(1/2.000) for Anti-BV. 4. No particular results were shown in the CBC test. 5. Observation of changes in the organ tissues, Anti-BV was found to suppress blood stasis in the liver and inhibit necrosis of the cells. Conclusion : Above results suggest that Anti-BV doesn't cause any toxic responses in the body and works as an anti-body to the bee venom. Further studies must be followed to secure the findings.
4 Title
Keywords oligonucleotide microarray; CTF-HAS; gene expression; SNU484
Author(s) Lee, Kyung-Min; Lim, Seong-Chul; Jung, Tae-Young; Seo, Jung-Chul; Han, Sang-Won
 Abstract Objectives : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as SNU484 gastric cancer cell lines. Oligonucleotide microarray approach were employed to screen the differential expression genes. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. Cells were treated with various concentrations of CTF-HAS(0.1, 0.5, 1.5, 10, 20mg/ml) for 24 h. Cytotoxicity was tested by MTT assay. To screen the differentially expressed genes in cancer cells, cells were treated with 1.5mg/ml of CTF-HAS. For oligonucleotide microarry assay, total RNA was used for gene expression analysis using oligonucleotide genechip (Human genome U133 Plus 2.0., Affimatrix Co.). Results : It has no cytotoxic effects on HepG2 cells in all concentration (0.1, 0.5, 1.5, 10,20mg/ml). More than twofold up-regulated genes were 5 genes. The number of more than twofold down-regulated genes was 10. Discussion : This study showed the screening of CTF-HAS mediated differentially regulated genes using combined approaches of oligonucleotide microarray. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.
5 Title
Keywords Bee Venom Herbal Acupuncture; LD50; manufacturing process; toxin; venom
Author(s) Jang, Seong-Bong; Choi, Young-Kwon; Kwon, Ki-Rok
 Abstract Objectives : This experiment was conducted to reevaluate $\small{LD_{50}}$ of Korean bee venom acupuncture as many changes have occurred over the years. Methods : ICR mice were used as the experiment animals and bee venom acupuncture was manufactured under the protocols of Korean Institute of herbal Acupuncture. Based on the previous reports, experiment was divided into pre and main sections. Results : 1. Presumed $\small{LD_{50}}$ value is at 5.25mg/kg 2. Deaths of experiment animals occurred within 48 hours. 3. Reduced toxicity of the bee venom acupuncture is likely to be the results of more refined manufacturing process and production. Conclusion : Comparing with the values of the previous results, toxicity of the bee venom acupuncture showed significant changes and more accurate findings on $\small{LD_{50}}$ value must be accomplished to lead further studies on the bee venom acupuncture
6 Title
Keywords Hominis Placenta; Herbal Acupuncture; Menstrual Cramps; Visual Analogue Scale
Author(s) Kang, Wee-Chang; Cho, Jung-Hyo; Lee, Yeon-Weol; Son, Chang-Gue; Cho, Chong-Kwan; Yoo, Hwa-Seung
 Abstract Purpose : The purpose of this study was to identify the effects of Hominis Placenta Herbal Acupuncture(HPA) combined with Acupuncture compared with Acupuncture therapy. Methods : Data was collected from October 1st 2004 to February 28th 2005. A total of 8 women participated in this study. Of all subjects, 4 and 4 subjects were assigned to the experimental and the control group respectively. Subjects were treated three times a week. We used Visual Analogue Scale(VAS) for evaluating the effects of HPA. Results : There showed statistically boardline significance between the experimental group and control group(p=0.057). Conclusion : The results showed HPA has significant effects on menstrual cramps.
7 Title
Keywords antihyperlipidemic; antioxidant; samhwangsasimtang; aqua-acupuncture; B18; CV12
Author(s) Lee, Eun; Lee, Joon-Moo
 Abstract Effects of Samhwangsasimtang aqua-acupuncture at gansoo($\small{B_{18}}$) and chungwan($\small{CV_{12}}$) on antihyperlipidemic and antioxidant were investigated in rat fed high fat diet. Concentrations of triglyceride, free fatty acids, lipoprotein and glucose in plasma showed a tendency to decrease in the aqua-acupuncture groups. In plasma lipid composition, total cholesterol and LDL- cholesterol showed a tendency to decrease in aqua-acupuncture groups, however the values of HDL-cholesterol showed no significantly different in the treatment groups. Concentration of thiobarbituric acid reactive substances(TBARS) in plasma and liver showed a low in the aqua-acupuncture groups. The values of glutathione peroxidase(GSH-Px) and catalase(CAT) activity showed a tendency to increase in aqua-acupuncture groups. However the values of superoxide dismutase(SOD) activity showed no significantly different in the treatment groups.
8 Title
Keywords Herbal-acupuncture; Jungsongouhyul; JSO; whiplash injury; traffic accident
Author(s) Seol, Hyun; Song, Beom-Ryong; Sin, Min-Seop; Yook, Tae-Han
 Abstract Objectives : To examine the effects of JSO multi-treatment for whiplash injury patients by traffic accident. Interventions : Nonrandomized, Nonblinded compartson of the JSO+Acupuncture and Acupuncture Treatment. Main Outcome Measures : Subjective evaluation was followed by Clinical Grade and VAS after 5 times treatments. The SPSS 10.0 for windows was used to analyze the date and the Wilcoxon signed rank test and Mann-Whitney U-testwere used to verify the results. Results : The following results were obtained ; 1. Clinical Grade of the JSO+Acupuncture treatment was centralized to Gr II(50%) before treatment. After 5 times treatments, it was centralized to Gr I(58.3%). Also Clinical Grade was significantly changed from GR ll to Gr I(p<0.0002). 2. Clinical Grade of the Acupuncture treatment was centralize(d) to Gr II(54.2%) before treament. After 5 times treament, it was tend to cenualize to Gr I(50%). But Clinical Grade was still remained at Gr II(p<0.001) 3. VAS of change between JSO+Acupuncture and Acupuncture treatment, Vas of JSO+Acupuncture was significantly decreased (p<0.003). C onclusion : It is suggested that JSO multi-treatment has development-effectiveness on whiplash injury patients by traffic accident.
9 Title
Keywords Needle; Needle tip; poor needle sensation; scanning electron microscope; Herbal Acupuncture
Author(s) Park, Won-Pil; Kim, Hyun-Do; Kwon, Ki-Rok
 Abstract Objectives : This study was conducted to observe the tip of needles which induce poor needle sensation upon injection of herbal acupuncture. Methods : Among the syringes used for herbal acupuncture, needles which cause poor sensation were collected and evaluated by SEM (scanning electron microscope) for changes in structure, existence of impure matters, physical damage, and etc. Results : 1. Various forms contributed to poor needle sensation. Bent needle body, damaged or crooked needle tip, and blunted tip 2. Poor needles could be made during the manufacturing process, during insertion of the needle into the vial(except for the lubricants), and repeated procedures with one needle at different regions. Conclusion : Poor needles induce unnecessary pain and discomfort not only to the patients but also to administrators during injection. Herbal acupuncture is a treatment technique injecting herbal extract on the meridian points, and strict quality check must be enforced to prevent occurrence of poor needles.
10 Title
Keywords six kinds of belly-ache; DongUiBoGam; acupuncture & moxibustion treatment
Author(s) Lee, Joon-Moo; Ji, Jun-Hwan
 Abstract Objectives : The purpose of this study is as follows. We classify belly-ache into six kinds as mentioned in DongUiBoGam (東醫寶鑑), and are going to present each acupuncture & moxibustion treatment. Methods : For the purpose of looking for each treatment, we referred to a large number of literature for belly-ache treatment from ancient to malearn. Results : The six kinds of belly-ache have each treatment above all, in treatment of belly-ache due to cold-belly-ache (寒腹痛) and hotbelly-ache (熱腹痛) have pain in the formable of ache part. Therefore, general point such as CVl2, CV8, ST36, Extra Meridian are used in turn. Also bad-blood-belly ache and many kinds of belly-ache such as BL18, BL17, LR2 are mainly used much in turn. Especially CV is in common use. Conclusions : we conclude that six kinds of belly-ache have each different acupuncture & moxibustion points and treatment, so if we follow each treatment we might obtain more higher treatment rate of belly-ache.