• [Archive]
  • Journal of Pharmacopuncture
  • pISSN : 2093-6966
  • eISSN : 2234-6856
  • DB Construction : 59 Issues, 667 Articles
1 Title
Keywords antioxidant activity; cultivated wild ginseng; superoxide; hydroxyl radical scavenging
Author(s) Rhim, Tae-Jin; Jeong, Hee-Sun; Kim, Young-Jin; Kim, Doo-Young; Han, Young-Ju; Kwon, Hae-Yon; Kwon, Ki-Rok
  Abstract Objectives : The objective of this study was to compare the antioxidant effects among cultivated wild ginseng and ginseng extracts. Methods : In vitro antioxidant activities were examined by superoxide and hydroxyl radical scavenging activities of ginseng and cultivated wild ginseng extracts. Results : 1. In the superoxide radical scavenging activities of ginseng and cultivated wild ginseng extracts, antioxidant activities of cultivated wild ginseng extracts was showed higher than cultivated ginseng in the concentration of 0.25 and . 2. In the hydroxyl radical scavenging activities of ginseng and cultivated wild ginseng extracts, antioxidant activities of cultivated wild ginseng extracts was showed higher than cultivated ginseng in the concentration of 1.0, 2.5, and . Conclusions : In summary, the results of this study demonstrate that cultivated wild ginseng extracts had higher antioxidant activities to cultivated ginseng.
2 Title
Keywords Ganoderma lucidum (GL); adipocytes; differentiation; energy expenditure
Author(s) Lee, Chae-Woo; Yoon, Hyun-Min; Kang, Kyung-Hwa
  Abstract In this study, the effects of Ganoderma lucidum (GL) on fat metabolism were performed in 3T3-L1 adipocytes. The effects of GL on 3T3-L1 preadipocytes differentiation were also examined. Our results showed that GL decreased the TG content by ORO staining. To elucidate the mechanism of the effects of GL on lowering TG content in 3T3-L1 adipocytes, we examined whether GL modulate the expressions of transcription factors and adipokines related to control of energy expenditure process because adipokines regulate adipocyte mass and increased expenditure may consume much TG in adipocytes. As a result, the expression of C/, C/, C/, and , genes, which induce the adipose differentiation and adipose-specific FAS, aP2, and adipsin genes, which compose fat formation were decreased. In addition, GL increased the expression of leptin, UCP2, adiponectin in 3T3-L1 adipocytes, resulting in energy homeostasis. In conclusion, GL could regulate transcript factor related to induction of adipose differentiation and control TG content by up-regulation of adipokines related to fat burn.
3 Title
Keywords Foot taeyang meridian muscle in human lower limb; $BL\; ^{36-40,\; 55-67}$; muscle; tendon; ligament; nerve
Author(s) Park, Kyoung-Sik
  Abstract Objective : This study was carried to identify the anatomical component of FTMM(Foot Taeyang Meridian Muscle) in human lower limb, and further to help the accurate application to real acupuncture. Methods : FTM at the surface of the lower limb was labelled with latex. And cadaver was stripped off to demonstrate muscles, nerves and the others and to display the internal structures of FTMM, being divided into outer, middle, and inner layer. Results : FTMM in human lower limb is composed of muscles, nerves, ligaments etc. The internal composition of the FTMM in human lower limb are as follows : 1) Muscle : Gluteus maximus. biceps femoris, semitendinosus, gastrocnemius, triceps calf, fibularis brevis tendon, superior peroneal retinacula, calcaneofibular ligament, inferior extensor retinaculum, abductor digiti minimi, sheath of flexor tendon at outer layer, biceps femoris, semimembranosus, plantaris, soleus, posterior tibialis, fibularis brevis, extensor digitorum brevis, flexor digiti minimi at middle layer, and for the last time semimembranosus, adductor magnus, plantaris, popliteus, posterior tibialis, flexor hallucis longus, dorsal calcaneocuboidal ligament at inner layer. 2) Nerve : Inferior cluneal nerve, posterior femoral cutaneous n., sural cutaneous n., proper plantar branch of lateral plantar n. at outer layer, sciatic nerve, common peroneal n., medial sural cutaneous n., tibial n. at middle layer, and for the last time tibial nerve, flexor hallucis longus branch of tibial n. at inner layer. Conclusions : This study proves comparative differences from already established studies from the viewpoint of constituent elements of FTMM in the lower limb, and also in the aspect of substantial assay method. We can guess that there are conceptional differences between terms (that is, nerves which control muscles of FTMM and those which pass near by FTMM) in human anatomy.
4 Title
Keywords Pharmacopuncture Solution; Carthmi Flos; Cnidii Rhizoma; Astragali Radix
Author(s) Kim, Hyung-Woo; Cho, Su-In; Kim, Il-Hwan
  Abstract Objective : This study was carried out to investigate protective effects of Pharmacopuncture Solutions (PSs) made by Carthmi Flos (CF), Cnidii Rhizoma (CR) and Astragali Radix (AR) on C6 glioma cells Methods : We investigated the effects of PSs on proliferation rates and types of C6 cells, and also investigated the effects on LDH release. In addition, protective effects of PSs on oxidative stress induced by hydrogen peroxide and SOD-like activities were also investigated. Results : PSs made by CF, CR and AR did not show cytotoxicity in various concentrations. CF-PS and AR-PS elevated levels of proliferation rates significantly. Treatment with CF-PS lowered level of LDH release in C6 cells. In addition, CF-PS and CR-PS showed protective effects on cell death induced by hydrogen peroxide respectively. Finally, CF-PS group showed high level of SOD-like activity compared to that in CR-PS group. Conclusion : These results suggest that CF-PS can accelerate proliferation of neuroglial cells, and has protective action against oxidative stress, which was involved in anti-oxidative effects such as SODlike activities. In addition, CR has protective effects against oxidative stress, and AR can accelerate proliferation of neuroglial cells.
5 Title
Keywords chronic tension-type headache; Pressure Pain Threshold; muscle tenderness
Author(s) Kim, Min-Jung; Kang, Wee-Chang; Hong, Kwon-Eui
  Abstract s. But muscular factors and psychological factors is supposed to be related with CTTH according to many other studies and pressure pain threshold(PPT) is used to measure muscular factors. Methods 1. We performed this study with 63 patients fulfilling the International Headache Societ criteria for chronic tension-type headache and 20 healthy control group and measured the PPT of temporal muscle and trapezius muscle. 2. We investigated the correlation between clinical characteristic and PPT. 3. Each of the CTTH groups and Control group is divided to four group again - HNP, Spondylosis, Sprain, Normal according to Cervical spine X-ray. Results 1. The PPT of temporal muscle and trapezius muscle in the CTTH is significantly lower than that of Control. 2. In CTTH group, the PPT has significant positive relation with duration of headache and continued time of headache. And the PPT has significant inverse relation with Frequency of headache and Level of headache. 3. In CTTH group, spondylosis group has the highest PPT and normal group is second. And there are significant difference between spondylosis group and the others. Conclusion : We found that PPT is strongly significant to measure muscular factor in CTTH.
6 Title
Keywords Herb drug medicine treatment; Functional Dyspepsia; Nepean Dyspepsia Index
Author(s) Lee, Jae-Jin; Son, Mi-Won; Hong, Kwon-Eui
  Abstract Objective : Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this research is to examine the equivalent effect of herb drug medicine treatment(H-D)and Over the Counter(OTC) for functional dyspepsia. Method : In this controlled study, we compared herb drug medicine(H-D) with Over the Counter(OTC) of functional dyspepsia. 30 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index(NDI-K) before and after treatments. Result : The results are summarized as follows. 1. In Herb drug medicine and Over the Counter groups, total key symptoms score of after treatment were significantly decreased and improve rate of key symptoms was higher than before treatment, but there were no statistical significance between two groups. 2. In Herb drug medicine and Over the Counter groups, each symptoms score of after treatment were significantly decreased and improve rate of key symptoms was higher than before treatment, but there were no statistical significance between two groups. 3. In Herb drug medicine and Over the Counter groups, quality of life score of after treatment were significantly decreased and improve rate of key symptoms was higher than before treatment, but there were no statistical significance between two groups. Conclusion : Herb drug medicine treatment(H-D) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.
7 Title
Keywords Papaver somniferum L; opium; narcotics; analgesics
Author(s) Lim, Chung-San; Han, Young-Ju; Kang, Kye-Sung; Lee, Kwang-Ho; Kim, Doo-Young; Kwon, Ki-Rok
  Abstract Objectives : This study was performed to developing orally administered analgesics and locally injected pharmacopuncture analgesics like opioids. Methods : Literary investigation on the origin of poppy (Papaver somniferum L) and other narcotics was conducted to examine the potential of developing orally administered analgesics and locally injected pharmacopuncture analgesics. Opium is a gum-like mass derived from air-dried white fluid of immature fruit of the poppy. Opium contains approximately 20 types of alkaloids including morphine, codeine, thebaine, papaverine and others. Natural opioids and synthetic alkaloid derivatives are the constituents of opioid analgesics and their effects and side-effects depend on the peculiarities of receptors. An extreme caution is required in the selection of proper dosage, proper analgesic types, and indications for successful pain management. Results and Discussion : With the enactment of "Narcotic control protocol", herbs such as cannibis and poppy are no longer available for use by Korean medicine doctors, and these doctors are faced with difficulty in managing severe pain in the clinical environment. A systematic consideration is inevitable for overcoming the limitation on these analgesics.
8 Title
Keywords Spinal Cord Injury; Sweet BV; Sensation; ASIA; Frankle classification
Author(s) Park, In-Sun; Yoon, Il-Ji
  Abstract Objective : Patients with spinal cord injury are increasing in numbers. However, there is no reliable treatment guide in both conventional & complementary medicine. Also, there are not much clinical case of patients with spina cord injury in oriental medical field. We investigated effect of sweet BV on subacute stage patient with spinal cord injury. Method : 31-year old female patient with spinal cord injury was treated with herb medicine(TID), electro arcupunture (BID), sweet BV injection(QOD), Physical treatment(QD), and conventional-medicine. Result : We had a satisfactory result with using sweet BV injection. The patient's ASIA grade improved from 34 to 52. And Frankle classification of the patient shifted from A to B. Conclusion : We reach a conclusion Using Sweet BV improve the sensation of patient with spinal cord injury. And more study about this disease is needed.
9 Title
Keywords Anaphylaxis; Sweet Bee Venom; melittin; clinical observation
Author(s) Kwon, Ki-Rok; Kang, Kye-Sung; Lee, Kwang-Ho; Lim, Chung-San; Jeong, Hee-Sun; Kwon, Hae-Yon
  Abstract Objectives : Sweet bee venom(SBV) is pure melittin, the main component of bee venom, made by removing another components through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. In the using SBV, 2 patients were experienced anaphylaxis by SBV. So, we reported the process of anaphylaxis and consider these situation. Methods : We observed 2 patients suffered from anaphylaxis after treated with SBV in the Korean Medical Hospital, Sangji University. Results : Though SBV was removed allergen from bee venom, it is not possible to complete prevention of anaphylactic shock in the clinics. So, Korean medical doctor using BV or SBV must be prepare the system consider a countermeasure by anaphylaxis.
10 Title
Keywords leech therapy; buerger's disease
Author(s) Kwak, Byung-Min; Hong, Kwon-Eui
  Abstract Objective : The purpose of this case is to show a case of buerger's disease improved by leech therapy. Methods : The patient received Leech Therapy and Oriental medical therapy(acupuncture and herb medicine). Result : We evaluate through visual analog scale(VAS), neuropathic total symptom score(TSS), fontaine grade and picture of patient's foot. Conclusion : Leech therapy and Oriental medical therapy had a good effect on buerger's disease.
11 Title
Keywords allergic rhinitis; Bee Venom Pharmacopuncture; acupuncture treatment
Author(s) Kim, Jae-Hong; Kim, Chang-Hwan
  Abstract Objective : This is a clinical report about allergic rhinitis patients. Method : The two patients were treated by Bee Venom Pharmacopuncture and needle acupuncture together from June 2007 to September 2007. Result : As using these treatments, all patients decreased in sneezing, rhinorrhea and nasal congestion notably. And further, all patients had no side effects. Conclusion : The results suggest that Bee Venom Pharmacopuncture and needle acupuncture have an useful effect on allergic rhinitis patients.
12 Title
Keywords Mountain cultivated wild ginseng; Pharmacopuncture; liver function; AST; ALT
Author(s) Kim, Young-Jin; Park, Do-Il; Kwon, Ki-Rok
  Abstract Mountain cultivated wild ginseng(MCWG) pharmacopuncture, which is known to have anti-cancer and anti-oxidation actions, was administered for clinical usage and changes in manifestations were observed on three patients suffering from pain attributed from liver dysfunctions. In two cases of hepatitis due to poisoning by drugs and one case of liver cirrhosis, long-term administration of MCWG pharmacopuncture yielded significant changes in AST and ALT, which are important indices for liver functions. Improved liver functions after the administration of MCWG pharmacopuncture suggest a need for investigation on future usage of MCWG pharmacopuncture on liver dysfunctions, hepatitis, liver cirrhosis, or liver cancer. Further studies on treating aforementioned disorders by MCWG pharmacopuncture are needed immediately.